Description

(3S,4R)-4-Aminotetrahydro-3-Furancarboxylic Acid CAS NO 797038-60-9 is a high-purity, non-proteinogenic amino acid derivative featuring a stereochemically defined tetrahydrofuran ring system. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of novel therapeutics with precise biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of peptide mimetics, enzyme inhibitors, and other complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and neurological disorder research.
• Peptidomimetic Chemistry: Used to construct conformationally constrained peptide analogs, enhancing metabolic stability and receptor selectivity.
• Protease Inhibitor Development: Serves as a core scaffold in the design of inhibitors for various proteolytic enzymes.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a tool compound for probing biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical transformations.
• API Process Development: Integrated into scalable synthetic routes for the commercial production of active pharmaceutical ingredients.

Basic Information

Product Name	(3S,4R)-4-Aminotetrahydro-3-Furancarboxylic Acid
CAS No.	797038-60-9
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(3S,4R)-4-Aminooxolane-3-carboxylic acid; (3S,4R)-4-Aminotetrahydrofuran-3-carboxylic Acid; 4-Amino-3-furancarboxylic acid, tetrahydro-, (3S,4R)-; cis-4-Aminotetrahydrofuran-3-carboxylic acid; (3S,4R)-4-Amino-3-tetrahydrofurancarboxylic Acid; ATFC; 4-Aminotetrahydro-3-furancarboxylic Acid (specified stereochemistry)
EINECS	Contact for details

Quality Control

Our (3S,4R)-4-Aminotetrahydro-3-Furancarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.