Description

1-(Tetrahydro-2H-Pyran-4-Yl)Piperidin-4-Amine is a high-purity, versatile heterocyclic amine building block of significant importance in modern organic synthesis. Its unique fused bicyclic structure, combining piperidine and tetrahydropyran motifs, makes it a critical intermediate for constructing complex molecules with specific pharmacological profiles. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where its structural features can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new chemical spaces and synthesizing libraries of compounds for high-throughput screening.
• Material Science: Potential building block for specialty polymers, dyes, and advanced organic materials requiring specific amine functionality.

Basic Information

Product Name	1-(Tetrahydro-2H-Pyran-4-Yl)Piperidin-4-Amine
CAS No.	794471-13-9
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	4-Amino-1-(tetrahydro-2H-pyran-4-yl)piperidine; 1-(Oxan-4-yl)piperidin-4-amine; 4-Piperidinamine, 1-(tetrahydro-2H-pyran-4-yl)-; THP-Piperidin-4-amine; 794471-13-9; 1-(Tetrahydro-2H-pyran-4-yl)-4-piperidinamine; 1-(Tetrahydropyran-4-yl)piperidin-4-amine
EINECS	Contact for details

Quality Control

Our 1-(Tetrahydro-2H-Pyran-4-Yl)Piperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with material produced under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.