Description

(2R)-Rel-6-Fluoro-3,4-Dihydro-2-[(2S)-2-Oxiranyl]-2H-1-Benzopyran CAS NO 793669-26-8 is a high-purity, chiral benzopyran derivative featuring a fused oxirane (epoxide) ring, making it a valuable advanced pharmaceutical intermediate. Its precise stereochemistry and reactive epoxide moiety are critical for synthesizing complex, biologically active molecules, particularly in the development of novel therapeutic agents. This compound is primarily targeted at research institutions and pharmaceutical manufacturers engaged in the discovery and production of new drugs, especially those focusing on cardiovascular and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Stereoselective Synthesis: Employed in asymmetric synthesis to construct complex molecular architectures with defined chirality.
• Preclinical Development: Serves as a critical material for producing batches of candidate drugs for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(2R)-Rel-6-Fluoro-3,4-Dihydro-2-[(2S)-2-Oxiranyl]-2H-1-Benzopyran
CAS No.	793669-26-8
Molecular Formula	C13H13FO3
Molecular Weight	236.24 g/mol
Synonyms	6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-(2R)-2H-1-benzopyran; (2R,2'S)-6-Fluoro-3,4-dihydro-2'-(oxiran-2-yl)-2H-spiro[benzopyran-2,2'-oxirane]; Rel-(2R,2'S)-6-Fluoro-3,4-dihydrospiro[2H-1-benzopyran-2,2'-oxirane]; Fluorinated Spirocyclic Benzopyran Epoxide; Chiral Benzopyran Epoxide Intermediate
EINECS	Contact for details

Quality Control

Our production of (2R)-Rel-6-Fluoro-3,4-Dihydro-2-[(2S)-2-Oxiranyl]-2H-1-Benzopyran adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including chiral purity and impurity profiling. Certificates of Analysis (COA) detailing identity, assay, and purity are provided with each shipment. We support development and commercial projects with quality standards suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.