Description

Bicyclo[2.2.1]Heptane-2-Acetic Acid, 2-Hydroxy-1,7,7-Trimethyl- (9Ci) CAS NO 790648-13-4 is a high-purity, functionalized bicyclic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique sterically hindered structure and hydroxyl-acetic acid functionality make it critical for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its rigid bicyclic structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control enantioselectivity in critical bond-forming reactions.
• Fragrance and Flavor Chemistry: The camphor-like backbone of the bicyclo[2.2.1]heptane (norcamphor) system makes it a potential intermediate for synthesizing high-value aroma chemicals and flavor compounds.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique thermal and mechanical properties due to its rigid, polycyclic structure.
• Academic and R&D Laboratories: Employed as a standard or building block in methodological studies and for the total synthesis of complex natural products.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Acetic Acid, 2-Hydroxy-1,7,7-Trimethyl- (9Ci)
CAS No.	790648-13-4
Molecular Formula	C12H20O3
Molecular Weight	212.29 g/mol
Synonyms	2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-acetic acid; (1R,2R,4R)-2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-acetic acid (for specific enantiomer); 2-Hydroxynorcamphor-2-acetic acid; Trimethylbicycloheptane hydroxyacetic acid; Bicyclo[2.2.1]heptane-2-acetic acid, 2-hydroxy-1,7,7-trimethyl-; Norcamphor acetic acid derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetic Acid, 2-Hydroxy-1,7,7-Trimethyl- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.