Description

4-Oxa-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,3-(1,1-Dimethylethyl)-6-Methyl-7-Oxo-,trans-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic β-lactam structure. This compound is valued for its role as a critical building block in the synthesis of novel β-lactam antibiotics and other specialized active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel β-lactam antibiotic candidates.
• API Development: Used as a building block for constructing complex molecular architectures in active pharmaceutical ingredient (API) process development.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies in antimicrobial drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a protected or functionalized azabicyclic core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Oxa-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,3-(1,1-Dimethylethyl)-6-Methyl-7-Oxo-,trans-(9Ci)
CAS No.	790629-39-9
Molecular Formula	C12H17NO4
Molecular Weight	239.27 g/mol
Synonyms	trans-3-(tert-Butyl)-6-methyl-7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (2S,3S,5R)-3-(tert-Butyl)-6-methyl-7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 790629-39-9; 4-Oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-(1,1-dimethylethyl)-6-methyl-7-oxo-, (2S,3S,5R)-; Bicyclic β-lactam intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.