Description

4H-Pyran-4-One,2-Ethyltetrahydro-3-Methyl-6-Phenyl-,(2S,3R,6S)-(9Ci) is a high-purity, stereochemically defined chiral compound, serving as a critical advanced intermediate in complex organic syntheses. Its precise stereochemistry makes it an invaluable building block for the development of pharmaceuticals and fine chemicals where specific molecular orientation is essential for biological activity. This product is primarily targeted at research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides where the specific isomer can influence efficacy and environmental impact.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals requiring defined stereochemistry.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate R&D centers exploring new synthetic methodologies and compound libraries.
• Process Chemistry & Scale-Up: Provides a consistent starting point for optimizing and scaling the manufacture of chiral target molecules from lab to pilot plant.

Basic Information

Product Name	4H-Pyran-4-One,2-Ethyltetrahydro-3-Methyl-6-Phenyl-,(2S,3R,6S)-(9Ci)
CAS No.	790221-62-4
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	(2S,3R,6S)-2-Ethyl-3-methyl-6-phenyltetrahydro-4H-pyran-4-one; (2S,3R,6S)-2-Ethyl-3-methyl-6-phenyl-4H-pyran-4-one; 2-Ethyl-3-methyl-6-phenyltetrahydro-4H-pyran-4-one (specified stereoisomer); Tetrahydro-4H-pyran-4-one, 2-ethyl-3-methyl-6-phenyl-, (2S,3R,6S)-; (2S,3R,6S)-2-Ethyltetrahydro-3-methyl-6-phenyl-4H-pyran-4-one; A chiral dihydropyranone derivative.
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS to confirm identity, isomeric purity, and chemical purity. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request, supporting compliance in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2S,3R,6S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.