Description

2H-Pyran-2-Ol,4-(Dimethylamino)Tetrahydro-6-Methyl-,[2S-(2Alpha,4Beta,6Beta)]-(9Ci) CAS NO 790181-41-8 is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its complex molecular architecture, featuring a functionalized pyran ring system with a dimethylamino group, making it a versatile building block for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new-generation pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & R&D Laboratories: A valuable compound for methodological studies in organic chemistry, particularly those focusing on heterocyclic chemistry and stereoselective transformations.

Basic Information

Product Name	2H-Pyran-2-Ol,4-(Dimethylamino)Tetrahydro-6-Methyl-,[2S-(2Alpha,4Beta,6Beta)]-(9Ci)
CAS No.	790181-41-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2S,4R,6R)-4-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-ol; 4-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-ol (2S,4R,6R)-; Tetrahydro-4-(dimethylamino)-6-methyl-2H-pyran-2-ol, (2S,4R,6R)-; (2S,4R,6R)-4-(N,N-Dimethylamino)-6-methyltetrahydropyran-2-ol; CAS 790181-41-8; Chiral Pyranol Derivative; DMAP Derivative Intermediate.
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-Ol,4-(Dimethylamino)Tetrahydro-6-Methyl-,[2S-(2Alpha,4Beta,6Beta)]-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.