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4-Bromo-7-Methoxy-2-(2-Methyl-1,3-Dioxolan-2-Yl)-1-Benzofuran CAS NO 784189-79-3


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CAS No.:784189-79-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-7-Methoxy-2-(2-Methyl-1,3-Dioxolan-2-Yl)-1-Benzofuran is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzofuran core functionalized with bromine, methoxy, and a protected carbonyl group. This compound matters as a critical building block in modern organic synthesis, enabling the construction of complex molecules with precise stereochemistry and functional group compatibility. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with benzofuran-based pharmacophores.
  • Agrochemical Research: Used in developing new active ingredients for crop protection with specific biological activity.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and other transformations due to the reactive bromine substituent.
  • Material Science Research: Serves as a monomer or precursor for constructing organic electronic materials and functional polymers.
  • Chemical Reference Standard: Utilized in analytical laboratories for method development and quality control of related substances.

Basic Information

Product Name 4-Bromo-7-Methoxy-2-(2-Methyl-1,3-Dioxolan-2-Yl)-1-Benzofuran
CAS No. 784189-79-3
Molecular Formula C₁₅H₁₅BrO₄
Molecular Weight 339.18 g/mol
Synonyms 4-Bromo-7-methoxy-2-(2-methyl-1,3-dioxolan-2-yl)benzofuran; 2-(4-Bromo-7-methoxy-1-benzofuran-2-yl)-2-methyl-1,3-dioxolane; 4-Bromo-7-methoxy-2-(2-methyl-[1,3]dioxolan-2-yl)-benzofuran; 784189-79-3; 4-Bromo-7-methoxy-2-(2-methyl-1,3-dioxolan-2-yl)-1-benzofuran
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Quality Control

Our 4-Bromo-7-Methoxy-2-(2-Methyl-1,3-Dioxolan-2-Yl)-1-Benzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be sensitive to moisture and strong acids/bases; handle and store accordingly.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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