Description

1,3,4,5-Tetrahydro-Pyrano[4,3-B]Indole is a high-purity, fused heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring a pyran ring fused to an indole moiety, makes it a valuable scaffold for constructing complex pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Intermediate in the research and production of new generation crop protection agents and pesticides.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex polycyclic frameworks in academic and industrial laboratories.
• Material Science Research: Potential precursor for the development of organic electronic materials and specialty dyes due to its conjugated system.

Basic Information

Product Name	1,3,4,5-Tetrahydro-Pyrano[4,3-B]Indole
CAS No.	784143-97-1
Molecular Formula	C₁₁H₁₁NO
Molecular Weight	173.21 g/mol
Synonyms	1,3,4,5-Tetrahydro-2H-pyrano[4,3-b]indole; Pyrano[4,3-b]indole, 1,3,4,5-tetrahydro-; 2H-Pyrano[4,3-b]indole, 1,3,4,5-tetrahydro-; 1,2,3,5-Tetrahydro-4H-pyrano[4,3-b]indole; 4H-Pyrano[4,3-b]indole, 1,2,3,5-tetrahydro-; Tetrahydro-pyranoindole; Pyranoindole derivative
EINECS	Contact for details

Quality Control

Our 1,3,4,5-Tetrahydro-Pyrano[4,3-B]Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.