Description

4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Ol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a primary amine and a tertiary alcohol within a tetrahydropyran ring, makes it a valuable scaffold for constructing complex molecules. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, chiral ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Chiral Ligand/ Catalyst Precursor: Used to develop novel asymmetric catalysts and ligands for enantioselective synthesis, crucial for producing single-isomer compounds.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Peptidomimetics & Bioactive Molecules: The amino alcohol functionality is integral for creating peptide analogs and other bioactive compounds with improved metabolic stability.
• Polymer Modification: Can be used to introduce functional amine and hydroxyl groups into polymer chains for specialty materials.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Ol
CAS No.	783303-73-1
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	4-(Aminomethyl)-4-hydroxytetrahydropyran; 4-Hydroxy-4-(aminomethyl)tetrahydro-2H-pyran; 4-(Aminomethyl)-4-hydroxypiperidine (tautomer); 4-(Aminomethyl)tetrahydropyran-4-ol; 4-Pyranmethanamine, tetrahydro-4-hydroxy-; 4-Hydroxytetrahydropyran-4-ylmethanamine; Amino alcohol THP derivative; Chiral THP-amino alcohol
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent chiral integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.