Description

4-Bromo-3-Fluoro-Benzamidine is a high-purity, halogenated benzamidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate, enabling the construction of complex molecules for drug discovery and development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors, where its unique structure facilitates the creation of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of protease inhibitors and other small molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated aromatic core.
• Chemical Biology Probe Synthesis: Employed to create affinity-based probes for studying enzyme function and protein interactions.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and custom synthesis projects in R&D laboratories.

Basic Information

Product Name	4-Bromo-3-Fluoro-Benzamidine
CAS No.	780721-73-5
Molecular Formula	C7H6BrFN2
Molecular Weight	217.04 g/mol
Synonyms	4-Bromo-3-fluorobenzamidine; 3-Fluoro-4-bromobenzamidine; Benzenecarboximidamide, 4-bromo-3-fluoro-; 4-Bromo-3-fluoro-benzenecarboximidamide; 780721-73-5; 4-Br-3-F-BzA
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-Benzamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.