Description

2H-Pyran-3-Carboxamide,4-Aminotetrahydro-n-Hydroxy-,(3R,4R)-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the development of novel, biologically active molecules, offering precise structural control. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex heterocyclic compounds, particularly for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex heterocyclic scaffolds.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct molecules with defined three-dimensional configurations, crucial for modern medicinal chemistry.
• Chemical Research & Development: Serves as a valuable reference standard and starting material in academic and industrial R&D labs for exploring new synthetic pathways and methodologies.
• Process Chemistry Optimization: Used in scaling up synthetic routes from laboratory to pilot plant scale, aiding in the development of efficient and cost-effective manufacturing processes.
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents and herbicides with specific modes of action.

Basic Information

Product Name	2H-Pyran-3-Carboxamide,4-Aminotetrahydro-n-Hydroxy-,(3R,4R)-(9Ci)
CAS No.	780034-38-0
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	(3R,4R)-4-Amino-3-hydroxytetrahydro-2H-pyran-3-carboxamide; 4-Amino-3-hydroxy-tetrahydro-2H-pyran-3-carboxamide (3R,4R)-; (3R,4R)-4-Amino-3-hydroxytetrahydro-2H-pyran-3-carboxylic acid amide; Tetrahydro-4-amino-3-hydroxy-2H-pyran-3-carboxamide (3R,4R)-; 780034-38-0; (3R,4R)-rel-4-Amino-3-hydroxytetrahydro-2H-pyran-3-carboxamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.