Description

Ethanone, 2-Amino-1-(3-Hydroxycyclohexyl)-, cis- (9Ci) is a specialized chiral amino ketone building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both amino and hydroxy functional groups on a cyclohexyl scaffold, makes it a valuable precursor for constructing complex, biologically active molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for activity.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and Industrial Research: A valuable tool compound for methodological development in organic chemistry, including studies on stereoselective reactions.

Basic Information

Product Name	Ethanone, 2-Amino-1-(3-Hydroxycyclohexyl)-, cis- (9Ci)
CAS No.	780004-43-5
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	cis-2-Amino-1-(3-hydroxycyclohexyl)ethanone; 1-(3-Hydroxycyclohexyl)-2-aminoethanone, cis-; 2-Amino-1-(3-hydroxycyclohexyl)ethanone (cis-isomer); (1R,3S)-2-Amino-1-(3-hydroxycyclohexyl)ethanone (likely stereoisomer); Amino hydroxycyclohexyl ethanone; CAS 780004-43-5
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 2-Amino-1-(3-Hydroxycyclohexyl)-, cis- (9Ci) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol includes advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.