Description

1,4-Dioxane-2-Carboxylicacid,3,3,5-Trimethyl-,Ethylester,(2R,5R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid, functionalized 1,4-dioxane scaffold, which serves as a key intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, particularly in medicinal chemistry programs targeting complex molecular structures.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule influences biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis to induce enantioselectivity.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require incorporation of rigid, heterocyclic components.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in methodology development and the total synthesis of natural products.

Basic Information

Product Name	1,4-Dioxane-2-Carboxylicacid,3,3,5-Trimethyl-,Ethylester,(2R,5R)-Rel-(9Ci)
CAS No.	779333-47-0
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	(2R,5R)-3,3,5-Trimethyl-1,4-dioxane-2-carboxylic acid ethyl ester; Ethyl (2R,5R)-3,3,5-trimethyl-1,4-dioxane-2-carboxylate; rel-(2R,5R)-Ethyl 3,3,5-trimethyl-1,4-dioxane-2-carboxylate; 1,4-Dioxane-2-carboxylic acid, 3,3,5-trimethyl-, ethyl ester, (2R,5R)-rel-; (2R,5R)-rel-Ethyl 3,3,5-trimethyl-1,4-dioxane-2-carboxylate; 779333-47-0; Chiral 1,4-dioxane ester
EINECS	Contact for details

Quality Control

Every batch of this chiral intermediate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail critical parameters including chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality systems are designed to support cGMP and ISO standards for reliable and consistent material supply to the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.