Description

2-Bromo-5-Fluorophenylhydrazine Hcl is a high-purity halogenated phenylhydrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive hydrazine moiety adjacent to bromo and fluoro substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated phenyl ring.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and liquid crystals.
• Dyestuff and Pigment Manufacturing: Acts as a coupling agent for producing azo dyes and high-performance pigments with enhanced lightfastness.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research and diagnostic applications.
• Cross-Coupling Reactions: The bromo substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.

Basic Information

Item	Detail
Product Name	2-Bromo-5-Fluorophenylhydrazine Hydrochloride
CAS No.	776239-07-7
Molecular Formula	C6H5BrF2N2 • HCl
Molecular Weight	251.48 g/mol (Free base: 214.02 g/mol)
Synonyms	(2-Bromo-5-fluorophenyl)hydrazine hydrochloride; 2-Bromo-5-fluoro-phenylhydrazine HCl; 1-(2-Bromo-5-fluorophenyl)hydrazine hydrochloride; Hydrazine, (2-bromo-5-fluorophenyl)-, hydrochloride; 776239-07-7; 2-Br-5-F-C6H3-NHNH2•HCl
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluorophenylhydrazine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.