Description

1-[(4-Methoxyphenyl)Sulfonyl]Piperidine-4-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and sulfonyl hydrazide functional groups. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular scaffolds via reactions involving the reactive carbohydrazide moiety.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new synthetic pathways and structure-activity relationships (SAR).
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes under Good Manufacturing Practice (GMP) guidelines.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	1-[(4-Methoxyphenyl)Sulfonyl]Piperidine-4-Carbohydrazide
CAS No.	774575-27-8
Molecular Formula	C13H19N3O4S
Molecular Weight	313.37 g/mol
Synonyms	4-(Hydrazinecarbonyl)-1-[(4-methoxyphenyl)sulfonyl]piperidine; 1-(4-Methoxybenzenesulfonyl)piperidine-4-carbohydrazide; Piperidine-4-carbohydrazide, 1-[(4-methoxyphenyl)sulfonyl]-; 4-Carbohydrazido-1-(p-methoxyphenylsulfonyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-[(4-Methoxyphenyl)Sulfonyl]Piperidine-4-Carbohydrazide is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.