Description

7-Fluorochroman-4-Amine is a high-purity fluorinated chroman derivative, a key chiral building block in modern synthetic organic chemistry. Its value lies in its unique molecular scaffold, which combines a fluorine atom for metabolic stability with a chiral amine functionality for precise stereochemical control. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and environmental persistence.
• Asymmetric Catalysis: Serves as a precursor or ligand in asymmetric synthesis to induce chirality in target molecules.
• Material Science Research: Employed in the development of specialty chemicals and advanced organic materials.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	7-Fluorochroman-4-Amine
CAS No.	774163-31-4
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	4-Amino-7-fluorochroman; 7-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine; 7-Fluoro-4-chromanamine; 4-Amino-7-fluoro-3,4-dihydro-2H-chromene; 7-Fluoro-3,4-dihydro-2H-chromen-4-amine; 7-Fluorochroman-4-ylamine; 4-Amino-7-fluorochromane
EINECS	Contact for details

Quality Control

Our 7-Fluorochroman-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for advanced research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for chiral specific grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.