Description

2-Amino-3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid is a non-proteinogenic amino acid derivative featuring a tetrahydro-2H-pyran-4-yl side chain. This unique structure makes it a valuable chiral building block and intermediate for the synthesis of complex molecules. It is primarily sought after by pharmaceutical research and development organizations for applications in drug discovery and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Peptidomimetics: Used to incorporate constrained, ring-containing amino acid analogs into peptide chains to enhance metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Serves as a building block for synthesizing molecular probes to study enzyme mechanisms, protein-protein interactions, and biological pathways.
• Agrochemical Research: Potential intermediate in the development of new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Ligand Synthesis for Catalysis: Can be utilized to create novel chiral ligands for asymmetric synthesis, aiding in the production of enantiomerically pure compounds.

Basic Information

Item	Details
Product Name	2-Amino-3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid
CAS No.	773828-10-7
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	4-(2-Amino-2-carboxyethyl)tetrahydro-2H-pyran; 2-Amino-3-(tetrahydropyran-4-yl)propionic acid; (S)-2-Amino-3-(tetrahydro-2H-pyran-4-yl)propanoic acid (for enantiomer); THP-Alanine derivative; 4-(1-Amino-2-carboxyethyl)tetrahydropyran; 773828-10-7; 2-Amino-3-(oxan-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our production of 2-Amino-3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid adheres to stringent in-process controls and final release testing. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from advanced analytical techniques (HPLC, NMR, MS) are provided with every shipment. We support development and cGMP manufacturing needs with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% e.e. (for enantiomerically pure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.