Description

Ethanone, 1-(1,3-Dioxolan-2-Yl)-2,2,2-Trifluoro- (9Ci) CAS NO 773087-37-9 is a specialized fluorinated ketone derivative featuring a dioxolane-protecting group, making it a valuable synthetic intermediate. This compound is engineered to introduce the trifluoroacetyl moiety into target molecules, a critical step for modifying physicochemical properties and enhancing metabolic stability in advanced materials and pharmaceuticals. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex, fluorine-containing molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) containing trifluoromethyl ketone groups, which are prevalent in drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoroacetyl group contributes to biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with unique thermal, optical, or surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for nucleophilic addition reactions, Grignard reactions, and as a precursor for heterocyclic compounds.
• Fluorine Chemistry Research: An essential tool for studying the effects of fluorine substitution on reaction mechanisms and molecular conformation in medicinal and synthetic chemistry.

Basic Information

Product Name	Ethanone, 1-(1,3-Dioxolan-2-Yl)-2,2,2-Trifluoro- (9Ci)
CAS No.	773087-37-9
Molecular Formula	C5H5F3O3
Molecular Weight	170.09 g/mol
Synonyms	2,2,2-Trifluoro-1-(1,3-dioxolan-2-yl)ethanone; 1-(1,3-Dioxolan-2-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1,3-dioxolan-2-yl)ethan-1-one; 2-(Trifluoroacetyl)-1,3-dioxolane; Trifluoroacetyldioxolane; 1,3-Dioxolane-2-carbaldehyde, trifluoroacetyl-; (1,3-Dioxolan-2-yl)(trifluoro)methanone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(1,3-Dioxolan-2-Yl)-2,2,2-Trifluoro- (9Ci) adheres to a strict quality management system to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.