Description

3-Buten-1-Amine,4-(4-Methoxyphenyl)-,(Z)-(9Ci) is a specialized chiral amine building block featuring a unique (Z)-configured butenyl side chain attached to a p-methoxyphenyl ring. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering a defined stereocenter and reactive amine and alkene functionalities for further derivatization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific stereochemical requirements for enhanced biological activity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	3-Buten-1-Amine,4-(4-Methoxyphenyl)-,(Z)-(9Ci)
CAS No.	771426-11-0
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(Z)-4-(4-Methoxyphenyl)-3-buten-1-amine; (Z)-4-(p-Methoxyphenyl)-3-buten-1-amine; (3Z)-4-(4-Methoxyphenyl)but-3-en-1-amine; (Z)-1-Amino-4-(4-methoxyphenyl)-2-butene; 4-(4-Methoxyphenyl)-(Z)-3-buten-1-amine; p-Methoxycinnamylamine (Z-isomer); (Z)-Cinnamylamine, 4'-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Buten-1-Amine,4-(4-Methoxyphenyl)-,(Z)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (Z-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.