Description

L-Alanine, 3-(Hydroxydimethylsilyl)- (9Ci) is a specialized organosilicon-modified amino acid derivative, offering a unique bifunctional structure that combines the biological compatibility of alanine with the versatile reactivity of a silanol group. This compound is engineered for advanced material science applications where precise surface modification and controlled organic-inorganic interface engineering are critical. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced polymer sectors seeking to develop novel hybrid materials, bioactive coatings, or sophisticated drug delivery systems.

Application

• Bioconjugation and Peptide Synthesis: Serves as a key building block for introducing silyl groups into peptides or proteins, enabling subsequent surface immobilization or cross-linking strategies.
• Surface Modification Agent: Used to functionalize silica, glass, or metal oxide surfaces with bioactive organic layers, enhancing biocompatibility for medical devices or biosensors.
• Advanced Polymer Precursor: Acts as a monomer or cross-linker in the synthesis of novel silicone-based hybrid polymers with tailored mechanical and biological properties.
• Drug Delivery Systems: Incorporated into the design of prodrugs or nanocarriers where the silanol group facilitates targeted release or improved stability.
• Chromatography Media: Employed in the development of specialized stationary phases for affinity chromatography or chiral separations.
• Adhesive and Sealant Formulations: Functions as an adhesion promoter in high-performance silicone systems requiring strong bonding to organic substrates.

Basic Information

Product Name	L-Alanine, 3-(Hydroxydimethylsilyl)- (9Ci)
CAS No.	770738-48-2
Molecular Formula	C5H13NO3Si
Molecular Weight	163.25 g/mol
Synonyms	3-(Hydroxydimethylsilyl)-L-alanine; L-2-Amino-3-(hydroxydimethylsilyl)propanoic acid; (2S)-2-Amino-3-(hydroxydimethylsilyl)propanoic acid; Silanediol, dimethyl-, 1-(2-amino-1-carboxyethyl)-, (S)-; Alanine, 3-(hydroxydimethylsilyl)-, L-; Silylated L-Alanine; Organosilicon amino acid
EINECS	Contact for details

Quality Control

Every batch of L-Alanine, 3-(Hydroxydimethylsilyl)- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chiral purity verification and impurity profiling, to meet the exacting standards required for advanced synthetic chemistry. Certificates of Analysis (COA) detailing specific batch results for identity, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% (L-isomer)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.