Description

2H-Pyran-2-One,Tetrahydro-4,5-Dimethyl-6-(1-Methylethyl)-,(4R,5R,6S)-Rel-(9Ci) CAS NO 770729-50-5 is a high-purity, stereochemically defined lactone derivative with significant utility in advanced organic synthesis. This compound serves as a critical chiral building block for the development of complex molecules, offering precise control over stereochemistry in downstream reactions. It is primarily sought by pharmaceutical R&D and fine chemical sectors for applications requiring high enantiomeric purity and reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex, stereospecific drug molecules.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development and testing of new asymmetric catalytic systems.
• Fragrance and Flavor Chemistry: Serves as a precursor for the synthesis of specific lactone-based aroma compounds, contributing to complex scent and flavor profiles.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereoisomerically pure agrochemicals and plant growth regulators.
• Material Science Monomer: Potential use as a specialized monomer for creating polymers with unique structural or chiral properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis and natural product total synthesis.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-4,5-Dimethyl-6-(1-Methylethyl)-,(4R,5R,6S)-Rel-(9Ci)
CAS No.	770729-50-5
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(4R,5R,6S)-4,5-Dimethyl-6-(propan-2-yl)tetrahydro-2H-pyran-2-one; (4R,5R,6S)-rel-4,5-Dimethyl-6-isopropyltetrahydro-2H-pyran-2-one; 6-Isopropyl-4,5-dimethyltetrahydro-2H-pyran-2-one (rel-(4R,5R,6S)-form); Tetrahydro-4,5-dimethyl-6-(1-methylethyl)-2H-pyran-2-one, (4R,5R,6S)-rel-; Lactone derivative of a substituted tetrahydropyran.
EINECS	Contact for details

Quality Control

Our production of this chiral lactone adheres to strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including Chiral HPLC, GC/MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.