Description

Cyclopenta[C]Pyran-1(3H)-One, Hexahydro-6-Hydroxy-7-(Hydroxymethyl)-4-Methyl-, (4R,4Ar,6S,7S,7As)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex polycyclic structure and multiple functional groups, making it a critical building block in sophisticated organic synthesis. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. CAS No. 767340-95-4.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Organic Synthesis Building Block: Utilized in multi-step synthesis for constructing intricate polycyclic frameworks due to its fused cyclopentapyranone core.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity and defined molecular architecture.

Basic Information

Item	Details
Product Name	Cyclopenta[C]Pyran-1(3H)-One, Hexahydro-6-Hydroxy-7-(Hydroxymethyl)-4-Methyl-, (4R,4Ar,6S,7S,7As)- (9Ci)
CAS No.	767340-95-4
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(4R,4aR,6S,7S,7aS)-Hexahydro-6-hydroxy-7-(hydroxymethyl)-4-methyl-1H-cyclopenta[c]pyran-1-one; (4R,4aR,6S,7S,7aS)-Hexahydro-6-hydroxy-7-(hydroxymethyl)-4-methylcyclopenta[c]pyran-1(3H)-one; Rel-(4R,4aR,6S,7S,7aS)-Hexahydro-6-hydroxy-7-(hydroxymethyl)-4-methyl-1H-cyclopenta[c]pyran-1-one; Cyclopenta[c]pyran-1(3H)-one, hexahydro-6-hydroxy-7-(hydroxymethyl)-4-methyl-, (4R,4aR,6S,7S,7aS)-; 767340-95-4; Advanced Pharmaceutical Intermediate (API) Building Block; Chiral Cyclopentapyranone Derivative
EINECS	Contact for details

Quality Control

Our Cyclopenta[C]Pyran-1(3H)-One, Hexahydro-6-Hydroxy-7-(Hydroxymethyl)-4-Methyl-, (4R,4Ar,6S,7S,7As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.