Description

6-Amino-4-{2-[(2-Chlorobenzyl)Oxy]Phenyl}-3-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 767299-82-1. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry research and development. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

This specialized intermediate is designed for high-value synthesis applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: A key precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Development: Serves as a critical material for scaling up and optimizing synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of novel chemical entities for clients.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic reactions and bioactivity.

Basic Information

Product Name	6-Amino-4-{2-[(2-Chlorobenzyl)Oxy]Phenyl}-3-Phenyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	767299-82-1
Molecular Formula	C26H19ClN4O2
Molecular Weight	454.91 g/mol
Synonyms	6-Amino-4-[2-[(2-chlorophenyl)methoxy]phenyl]-3-phenyl-1,4-dihydro-5-cyanopyrano[2,3-c]pyrazole; 6-Amino-4-(2-((2-chlorobenzyl)oxy)phenyl)-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-[2-[(2-chlorophenyl)methoxy]phenyl]-3-phenyl-; Pyrano[2,3-c]pyrazole derivative (CAS 767299-82-1); 6-Amino-3-phenyl-4-(2-((2-chlorobenzyl)oxy)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Quality is verified through analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.