Description

3-Bromo-4-Hydroxybenzamidine is a high-purity benzamidine derivative, a crucial building block in modern organic synthesis and pharmaceutical research. Its unique structure, featuring both a bromo substituent and a hydroxy group on the aromatic ring, makes it a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and life science industries for developing novel enzyme inhibitors and therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of serine protease inhibitors, which are relevant for treating cardiovascular, inflammatory, and oncological conditions.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides and fungicides, leveraging its bioactive benzamidine core.
• Biochemical Tool Compound: Used in enzymatic assays and as a reference standard in proteomics and drug discovery research.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, enabling further functionalization.
• Material Science Precursor: Potential intermediate for synthesizing functionalized polymers or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-4-Hydroxybenzamidine
CAS No.	767261-36-9
Molecular Formula	C7H7BrN2O
Molecular Weight	215.05 g/mol
Synonyms	4-Hydroxy-3-bromobenzamidine; 3-Bromo-4-hydroxybenzenecarboximidamide; Benzamidine, 3-bromo-4-hydroxy-; p-Hydroxy-m-bromobenzamidine; (3-Bromo-4-hydroxyphenyl)methanimidamide; 767261-36-9; 3-Bromo-4-hydroxy-benzamidine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Hydroxybenzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.