Description

1-Bromo-4-(But-3-Yn-1-Yl)Benzene is a versatile aromatic building block featuring both a bromo substituent and a terminal alkyne functional group. This unique bifunctional structure makes it a critical intermediate in advanced organic synthesis, particularly for cross-coupling reactions and the construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create diverse heterocyclic systems.
• Material Science & OLED Development: Acts as a building block for conjugated polymers and small molecule organic semiconductors used in organic light-emitting diodes (OLEDs) and electronic devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Proteomics: Useful in click chemistry applications (e.g., CuAAC) for bioconjugation, labeling biomolecules, and developing molecular probes.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Bromo-4-(But-3-Yn-1-Yl)Benzene
CAS No.	765906-85-2
Molecular Formula	C10H9Br
Molecular Weight	209.08 g/mol
Synonyms	4-(3-Butyn-1-yl)bromobenzene; 1-Bromo-4-(3-butynyl)benzene; 4-Bromophenylbut-1-yne; p-Bromophenylbutyne; (4-Bromophenyl)but-1-yne; 4-(But-3-yn-1-yl)bromobenzene; 1-Bromo-4-(but-3-ynyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(But-3-Yn-1-Yl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.