Description

tert-Butyl 4-(2-Fluoro-5-((4-Oxo-3,4-Dihydrophthalazin-1-Yl)Methyl)Benzoyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for critical research and development applications. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery and scale-up projects.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Serves as a key raw material for the development and optimization of robust, scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed in the development of chemical probes and inhibitors for studying specific biological targets and pathways.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	tert-Butyl 4-(2-Fluoro-5-((4-Oxo-3,4-Dihydrophthalazin-1-Yl)Methyl)Benzoyl)Piperazine-1-Carboxylate
CAS No.	763114-04-1
Molecular Formula	C25H27FN4O4
Molecular Weight	466.51 g/mol
Synonyms	1,4-Dihydro-4-oxo-1-[[5-[(4-[[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl]carbonyl)-2-fluorophenyl]methyl]phthalazine; 1-[[5-[(4-[[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl]carbonyl)-2-fluorophenyl]methyl]-4(1H)-phthalazinone; tert-Butyl 4-[(2-fluoro-5-[(4-oxo-3,4-dihydro-1-phthalazinyl)methyl]benzoyl)]-1-piperazinecarboxylate; BOC-Piperazine Derivative (Fluorinated); 763114-04-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Fluoro-5-((4-Oxo-3,4-Dihydrophthalazin-1-Yl)Methyl)Benzoyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.