Description

Cyclopentaneacetic Acid, α-Amino-, Methyl Ester (9Ci) is a specialized chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. This compound, with CAS number 763078-53-1, is valued for its rigid cyclopentane backbone, which imparts conformational constraints critical for developing bioactive molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, peptide mimetics, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease targets.
• Peptidomimetics Synthesis: Used to construct conformationally restricted peptide analogs to enhance metabolic stability and receptor selectivity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides with potentially improved efficacy.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Academic & Institutional Research: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Cyclopentaneacetic Acid, α-Amino-, Methyl Ester (9Ci)
CAS No.	763078-53-1
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Methyl 2-amino-2-cyclopentylacetate; 2-Amino-2-cyclopentylacetic acid methyl ester; Methyl α-amino-cyclopentaneacetate; Cyclopentylglycine methyl ester; (Aminocyclopentyl)acetic acid methyl ester; 2-Cyclopentyl-2-aminoacetate methyl ester; Methyl 2-amino-2-cyclopentylacetate hydrochloride (salt form); (RS)-Methyl 2-amino-2-cyclopentylacetate
EINECS	Contact for details

Quality Control

Our Cyclopentaneacetic Acid, α-Amino-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.