Description

(4,4,4-Trifluorobutyl)-Guanidine is a high-purity fluorinated guanidine derivative, identified by CAS number 763077-38-9. This compound is a valuable synthetic intermediate, prized for its unique trifluorobutyl moiety which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme mechanisms and protein interactions, leveraging the guanidine group's strong binding affinity.
• Material Science: Employed in the research of advanced polymers and coatings, where fluorinated components can confer oil/water repellency and chemical resistance.
• Organic Synthesis: A versatile reagent for introducing the guanidine functional group into complex organic frameworks under controlled conditions.

Basic Information

Product Name	(4,4,4-Trifluorobutyl)-Guanidine
CAS No.	763077-38-9
Molecular Formula	C5H10F3N3
Molecular Weight	169.15 g/mol
Synonyms	4,4,4-Trifluorobutylguanidine; 1-(4,4,4-Trifluorobutyl)guanidine; Guanidine, N-(4,4,4-trifluorobutyl)-; 4,4,4-Trifluoro-1-butylguanidine; (4,4,4-Trifluorobutyl)guanidine; N-(4,4,4-Trifluorobutyl)guanidine; 763077-38-9; 4,4,4-Trifluorobutyl-guanidine
EINECS	Contact for details

Quality Control

Our (4,4,4-Trifluorobutyl)-Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures reliable material for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.