Description

2,6-Difluoro-Benzamidine is a high-purity, fluorinated benzamidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the amidine functional group into complex molecular architectures, particularly within pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated bioactive compounds.
• Chemical Biology & Proteomics: Serves as a precursor for affinity probes and activity-based protein profiling (ABPP) reagents targeting serine proteases.
• Material Science Research: Employed in the synthesis of novel polymers, ligands for catalysis, and advanced organic frameworks (MOFs/COFs).
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-Benzamidine
CAS No.	762229-49-2
Molecular Formula	C7H6F2N2
Molecular Weight	156.13 g/mol
Synonyms	2,6-Difluorobenzamidine; Benzenecarboximidamide, 2,6-difluoro-; 2,6-Difluorobenzenecarboximidamide; 2,6-Difluoro-benzenecarboximidamide; 2,6-Difluorobenzene-1-carboximidamide; 2,6-Difluoro-1-carbamimidoylbenzene; 2,6-Difluorophenylformamidine
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-Benzamidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.