Description

2-(Methylamino)Ethyl Methanethiosulfonate Hydrobromide is a specialized organosulfur compound that serves as a key reagent for the selective modification of cysteine residues in proteins and peptides. This matters for researchers and manufacturers requiring precise, reversible bioconjugation or the study of protein structure-function relationships. It is primarily needed by the pharmaceutical, biotechnology, and life sciences industries for applications in drug discovery, proteomics, and the development of antibody-drug conjugates (ADCs).

Application

• Bioconjugation Reagent: For the site-specific labeling and cross-linking of proteins and antibodies.
• Proteomics Research: Used in activity-based protein profiling (ABPP) and the study of cysteine reactivity.
• Antibody-Drug Conjugate (ADC) Development: Enables the controlled attachment of cytotoxic payloads to monoclonal antibodies.
• Enzyme Inhibition Studies: Acts as a reversible covalent inhibitor for thiol-containing enzymes.
• Peptide Synthesis: Employed in the synthesis and modification of peptides for therapeutic and diagnostic purposes.
• Material Science: Used to functionalize surfaces and nanomaterials with bioactive molecules.

Basic Information

Product Name	2-(Methylamino)Ethyl Methanethiosulfonate Hydrobromide
CAS No.	760998-74-1
Molecular Formula	C4H10BrNO2S2
Molecular Weight	248.16 g/mol
Synonyms	2-(Methylamino)ethyl methanethiosulfonate HBr; Methanethiosulfonic acid S-[2-(methylamino)ethyl] ester hydrobromide; MTSEA hydrobromide; (2-Methylaminoethyl) methanethiosulfonate hydrobromide; S-[2-(Methylamino)ethyl] methanethiosulfonate hydrobromide; 2-(Methylamino)ethyl MTS hydrobromide; Aminoethyl MTS derivative HBr salt
EINECS	Contact for details

Quality Control

Our 2-(Methylamino)Ethyl Methanethiosulfonate Hydrobromide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.