Description

(R)-2-Hydroxypropanimidamidehydrochloride is a chiral organic compound belonging to the class of amidine derivatives. This high-purity intermediate is critical for the synthesis of complex molecules where stereochemical integrity is paramount. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and as a building block for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a reagent or precursor in catalytic and stoichiometric asymmetric reactions to introduce the (R)-configured hydroxyamidine moiety.
• Chemical Research: Serves as a valuable standard and starting material in academic and industrial research for exploring new synthetic methodologies.
• Agrochemical Development: Potential intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for metal catalysis.

Basic Information

Product Name	(R)-2-Hydroxypropanimidamidehydrochloride
CAS No.	760109-40-8
Molecular Formula	C3H9N2O·HCl
Molecular Weight	140.58 g/mol
Synonyms	(R)-2-Hydroxypropionamidine hydrochloride; (R)-2-Hydroxypropanamidine hydrochloride; (R)-2-Hydroxypropaneamidine hydrochloride; (R)-2-Hydroxy-1-iminopropan-1-amine hydrochloride; (R)-Lactamidine hydrochloride; (R)-α-Hydroxypropionamidine hydrochloride; (2R)-2-Hydroxypropanimidamide hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxypropanimidamidehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.