Description

Bicyclo[2.2.2]Oct-5-En-2-One, 1-Methoxy-3,5-Dimethyl-, (1R,3S,4S)-Rel- (9Ci) is a chiral, functionalized bicyclic ketone building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought by research chemists and process development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-viral drug candidates.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where its stereochemistry can influence biological activity and environmental selectivity.
• Asymmetric Catalysis Ligand Synthesis: Acts as a core structure for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with specific optical or structural properties.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and stereochemical investigations.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for synthesizing complex, naturally-derived odorant molecules due to its bicyclic framework.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-5-En-2-One, 1-Methoxy-3,5-Dimethyl-, (1R,3S,4S)-Rel- (9Ci)
CAS No.	758724-07-1
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	(1R,3S,4S)-rel-1-Methoxy-3,5-dimethylbicyclo[2.2.2]oct-5-en-2-one; 1-Methoxy-3,5-dimethylbicyclo[2.2.2]oct-5-en-2-one, (1R,3S,4S)-rel-; rel-(1R,3S,4S)-1-Methoxy-3,5-dimethylbicyclo[2.2.2]oct-5-en-2-one; Bicyclo[2.2.2]oct-5-en-2-one, 1-methoxy-3,5-dimethyl-, (1R,3S,4S)-rel-; 758724-07-1; Chiral Bicyclic Ketone Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess, and key physical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material under an inert atmosphere at temperatures between 2°C and 8°C to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.