Description

1,1'-Bis[Bis(5-Methyl-2-Furanyl) Phosphino]Ferrocene, 98% Hiersophos-3 CAS NO 756824-22-3 is a high-purity, specialized organometallic ligand belonging to the ferrocenyl phosphine class. This compound is valued for its unique electronic and steric properties, which are critical for enabling highly selective and efficient catalytic transformations in advanced chemical synthesis. It is primarily sought after by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and fine chemicals through homogeneous catalysis, particularly in asymmetric hydrogenation and cross-coupling reactions.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal catalysts (e.g., Rh, Ru, Pd) in the enantioselective synthesis of pharmaceutical intermediates and active ingredients.
• Homogeneous Hydrogenation: For the selective reduction of prochiral olefins, ketones, and imines to produce optically pure compounds.
• Cross-Coupling Reactions: Facilitating C-C and C-X bond-forming reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination, under mild conditions.
• Academic & Industrial R&D: A key reagent for developing new catalytic methodologies and exploring structure-activity relationships in ligand design.
• Fine Chemical Synthesis: Production of complex, high-value molecules for agrochemicals, flavors, fragrances, and electronic materials.
• Catalyst Screening Libraries: Used in high-throughput screening to identify optimal catalyst systems for challenging synthetic transformations.

Basic Information

Product Name	1,1'-Bis[Bis(5-Methyl-2-Furanyl) Phosphino]Ferrocene, 98% Hiersophos-3
CAS No.	756824-22-3
Molecular Formula	C30H28FeO4P2
Molecular Weight	570.33 g/mol
Synonyms	Hiersophos-3; 1,1'-Bis[bis(5-methyl-2-furyl)phosphino]ferrocene; 1,1'-Ferrocenediyl-bis[bis(5-methyl-2-furyl)phosphine]; Bis(5-methyl-2-furyl)phosphinoferrocene; (R)-(+)-1,1'-Bis[bis(5-methyl-2-furyl)phosphino]ferrocene; (S)-(-)-1,1'-Bis[bis(5-methyl-2-furyl)phosphino]ferrocene; Josiphos-type ligand derivative
EINECS	Contact for details

Quality Control

Our 1,1'-Bis[Bis(5-Methyl-2-Furanyl) Phosphino]Ferrocene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive catalytic applications. Each lot is characterized by advanced analytical techniques, including NMR, HPLC, and elemental analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (argon or nitrogen) to prevent oxidation and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Assay (HPLC)	≥ 98.0%
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Solubility	Soluble in common organic solvents (e.g., THF, DCM, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.