Description

5-Bromo-2-Nitro-4-(Trifluoromethoxy)Aniline 98% is a high-purity, multi-functional aromatic amine derivative, distinguished by its bromo, nitro, and trifluoromethoxy substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex organic molecules. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its electron-withdrawing substituents.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced functional materials.
• Cross-Coupling Reactions: The bromo substituent makes it a valuable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-Bromo-2-Nitro-4-(Trifluoromethoxy)Aniline 98%
CAS No.	755030-18-3
Molecular Formula	C7H4BrF3N2O3
Molecular Weight	301.02 g/mol
Synonyms	4-Amino-3-bromo-6-nitrobenzotrifluoride; 4-Amino-3-bromo-1-nitro-2-(trifluoromethoxy)benzene; 3-Bromo-4-amino-6-nitrobenzotrifluoride; 5-Bromo-2-nitro-4-(trifluoromethoxy)benzenamine; 2-Nitro-5-bromo-4-(trifluoromethoxy)aniline; Benzenamine, 5-bromo-2-nitro-4-(trifluoromethoxy)-; 755030-18-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Nitro-4-(Trifluoromethoxy)Aniline 98% is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the declared 98% minimum purity and is free from critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.