Description

8-Methylchroman-4-Amine is a specialized organic compound belonging to the chroman amine class, serving as a key chiral building block and intermediate in advanced chemical synthesis. Its structural motif is highly valued for introducing specific stereochemistry and functional groups into target molecules, enabling the development of complex pharmacophores and fine chemicals. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular architecture is critical for bioactivity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its chroman core contributes to specific biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring its unique amine-substituted chroman structure.
• Academic and R&D Laboratories: Used as a reference standard and building block in medicinal chemistry and organic synthesis research programs.

Basic Information

Product Name	8-Methylchroman-4-Amine
CAS No.	754958-74-2
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	8-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine; 4-Amino-8-methylchroman; 8-Methyl-4-chromanamine; 2H-1-Benzopyran-4-amine, 8-methyl-3,4-dihydro-; 8-Methyl-3,4-dihydro-2H-chromen-4-amine
EINECS	Contact for details

Quality Control

Our 8-Methylchroman-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess (where applicable), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.