Description

Cyclohexanemethanamine, 4-(1-Methylethyl)- (9Ci) is a specialized chiral amine derivative of isophorone, featuring a cyclohexylmethanamine backbone with an isopropyl substituent. This compound matters as a high-value pharmaceutical intermediate and chiral building block for the synthesis of complex active molecules, offering a rigid, sterically defined structure crucial for asymmetric synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material science sectors seeking to introduce specific stereochemistry and conformational control into their target compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Catalyst Ligand: Serves as a backbone for developing proprietary chiral ligands used in enantioselective hydrogenation and cross-coupling reactions.
• Agrochemical Active Ingredient Synthesis: Building block for creating advanced herbicides and fungicides with improved stereospecific activity.
• Advanced Material Monomer: Used in the research and development of specialty polymers, such as polyamides or epoxy curing agents, requiring cycloaliphatic rigidity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex natural product analogs and chemical libraries.
• Flavor & Fragrance Chemistry: Intermediate for synthesizing high-value aroma chemicals with specific stereoisomeric profiles.

Basic Information

Product Name	Cyclohexanemethanamine, 4-(1-Methylethyl)- (9Ci)
CAS No.	749799-45-9
Molecular Formula	C10H21N
Molecular Weight	155.28 g/mol
Synonyms	4-Isopropylcyclohexylmethanamine; 4-(1-Methylethyl)cyclohexanemethanamine; (4-Isopropylcyclohexyl)methanamine; 4-Isopropyl-cyclohexanemethylamine; 1-(4-Isopropylcyclohexyl)methanamine; 4-(Propan-2-yl)cyclohexane-1-methanamine; 4-Isopropylcyclohexylmethylamine; α-Amino-4-isopropylmethylcyclohexane
EINECS	Contact for details

Quality Control

Our production of Cyclohexanemethanamine, 4-(1-Methylethyl)- adheres to stringent cGMP and ISO 9001 quality management standards. Each batch undergoes comprehensive analytical profiling, including chiral purity determination, to ensure it meets the exacting requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This amine is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) to prevent degradation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.