Description

1H-Pyrano[3,4-F]Indolizine-3,6,10(4H)-Trione, 7-Chloro-4-Ethyl-7,8-Dihydro-4-Hydroxy-, (4S)- is a high-purity, chiral synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the development of complex, biologically active molecules, particularly within pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic scaffolds. The precise stereochemistry and functional groups present make it a valuable precursor for targeted synthesis programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its complex fused-ring indolizine structure.
• Academic & Institutional R&D: Serves as a substrate for methodological studies in asymmetric synthesis, heterocyclic chemistry, and catalysis.
• Fine Chemical Synthesis: Employed in the multi-step production of specialty chemicals, dyes, and advanced materials requiring specific stereochemical configurations.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing reaction conditions for the manufacture of complex target molecules.

Basic Information

Product Name	1H-Pyrano[3,4-F]Indolizine-3,6,10(4H)-Trione, 7-Chloro-4-Ethyl-7,8-Dihydro-4-Hydroxy-, (4S)-
CAS No.	748799-31-7
Molecular Formula	C13H10ClNO5
Molecular Weight	295.67 g/mol
Synonyms	(4S)-7-Chloro-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione; 7-Chloro-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, (4S)-; (4S)-7-Chloro-4-ethyl-4-hydroxy-4,7,8,10-tetrahydro-1H-pyrano[3,4-f]indolizine-3,6,10-trione; CAS 748799-31-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.