Description

2(5H)-Furanone, 5-(1,1-Dimethylethyl)-3-Hydroxy- (9Ci) is a specialized furanone derivative, a high-value intermediate prized for its unique lactone structure and functional groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering chemists a versatile handle for constructing chiral centers and heterocyclic systems. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motifs contribute to biological activity.
• Fine Chemical Production: Serves as a versatile building block for synthesizing flavors, fragrances, and other specialty fine chemicals requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or modifying agent for creating novel polymers with specific degradation or functional properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2(5H)-Furanone, 5-(1,1-Dimethylethyl)-3-Hydroxy- (9Ci)
CAS No.	746639-69-0
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	5-tert-Butyl-3-hydroxy-2(5H)-furanone; 3-Hydroxy-5-tert-butylfuran-2(5H)-one; 5-(tert-Butyl)-3-hydroxy-2(5H)-furanone; 3-Hydroxy-5-(1,1-dimethylethyl)-2(5H)-furanone; 5-tert-Butyl-3-hydroxydihydrofuran-2-one; 746639-69-0; tert-Butyl hydroxy furanone
EINECS	Contact for details

Quality Control

Our 2(5H)-Furanone, 5-(1,1-Dimethylethyl)-3-Hydroxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound may be hygroscopic; keep container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.