Description

N,N'-(1R,2R)-1,2-Cyclohexanediyl Bis[N'-[3,5-Bis(Trifluoromethyl)Phenyl)] -Thiourea is a high-purity, chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a sophisticated organocatalyst and molecular recognition agent, enabling precise stereoselective transformations. It is essential for researchers and manufacturers in pharmaceutical development, asymmetric catalysis, and the synthesis of complex organic molecules.

Application

• Asymmetric Organocatalysis: A key chiral scaffold for catalyzing enantioselective reactions, such as Michael additions and aldol condensations.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Anion Recognition and Sensing: Serves as a selective receptor for anions in supramolecular chemistry and sensor development due to its thiourea binding sites.
• Ligand for Metal Complexes: Can act as a chiral ligand in coordination chemistry for creating metal-based catalysts.
• Material Science Research: Investigated for use in the development of advanced functional materials and polymers.
• Academic & Industrial R&D: A critical reagent for methodological studies in synthetic organic chemistry and process development.

Basic Information

Product Name	N,N'-(1R,2R)-1,2-Cyclohexanediyl Bis[N'-[3,5-Bis(Trifluoromethyl)Phenyl)] -Thiourea
CAS No.	743458-79-9
Molecular Formula	C24H20F12N4S2
Molecular Weight	656.56 g/mol
Synonyms	(1R,2R)-N,N'-Bis[3,5-bis(trifluoromethyl)phenyl]thiocarbamoyl-1,2-cyclohexanediamine; (1R,2R)-1,2-Diaminocyclohexane N,N'-bis[3,5-bis(trifluoromethyl)phenyl]thiourea; (R,R)-1,2-Cyclohexanediamine, N,N'-bis[3,5-bis(trifluoromethyl)phenyl]thiourea derivative; Chiral Bis(thiourea) Catalyst; Jacobsen Thiourea Analogue; Chiral Thiourea Organocatalyst; (R,R)-Cyclohexane-1,2-diyl bis(3-(3,5-bis(trifluoromethyl)phenyl)thiourea)
EINECS	Contact for details

Quality Control

Every batch of our chiral thiourea compound is produced and tested under strict quality management to ensure identity, purity, and enantiomeric excess. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to verify specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and relevant analytical data is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.