Description

Butanoic Acid, 4-Amino-2-(Aminomethyl)-3,3-Dimethyl- is a specialized, high-purity amino acid derivative with a unique sterically hindered structure. This compound matters as a critical building block and chiral intermediate in advanced pharmaceutical synthesis and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, particularly in neurological and metabolic disorder therapeutics.
• Peptidomimetic Research: Serves as a constrained, non-proteinogenic amino acid analog in peptide backbone modification and drug design.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Development: Employed in the synthesis of chelating ligands for asymmetric catalysis and metal complex formation.
• Bioconjugation and Linker Chemistry: Functional handle for creating cleavable linkers in antibody-drug conjugates (ADCs) and prodrugs.
• Fine Chemical Production: Building block for high-value specialty chemicals, flavors, and fragrances requiring precise molecular architecture.

Basic Information

Product Name	Butanoic Acid, 4-Amino-2-(Aminomethyl)-3,3-Dimethyl-
CAS No.	743400-04-6
Molecular Formula	C7H16N2O2
Molecular Weight	160.22 g/mol
Synonyms	4-Amino-2-(aminomethyl)-3,3-dimethylbutanoic acid; 3,3-Dimethyl-4-amino-2-aminomethylbutyric acid; (2R,4S)-4-Amino-2-(aminomethyl)-3,3-dimethylbutanoic acid (for specific stereoisomer); D-*threo*-4-Amino-2-(aminomethyl)-3,3-dimethylbutyric acid; AADMB; Sterically hindered diamino acid; 2-(Aminomethyl)-4-amino-3,3-dimethylbutyric acid
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 4-Amino-2-(Aminomethyl)-3,3-Dimethyl- is manufactured under strict quality management systems. We offer material suitable for research and GMP-grade applications, with purity typically exceeding 98% (by HPLC). Certificates of Analysis (COA) are provided with each batch, detailing identity, purity, chiral purity, and impurity profiles. Our quality commitment ensures compliance with relevant ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.