Description

2,5-Dimethoxyphenylzinc Iodide is an organozinc reagent, specifically an arylzinc halide, used as a key building block in organic synthesis. This compound matters for its role in facilitating efficient carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Negishi Cross-Coupling Reactions: Serves as a versatile nucleophilic partner for coupling with various aryl, heteroaryl, and vinyl halides or triflates.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-substituted structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science & OLED Precursors: Facilitates the synthesis of conjugated organic molecules and charge-transport materials for electronic applications.
• Academic & Contract Research: A valuable tool for methodological development and exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	2,5-Dimethoxyphenylzinc Iodide
CAS No.	738580-37-5
Molecular Formula	C8H9IO2Zn
Molecular Weight	353.44 g/mol
Synonyms	(2,5-Dimethoxyphenyl)zinc iodide; Zinc, (2,5-dimethoxyphenyl)iodo-; 1-Iodo-2,5-dimethoxybenzene zinc derivative; 2,5-Dimethoxybenzenezinc iodide; (2,5-Dimethoxyphenyl)iodozinc; Arylzinc reagent 738580-37-5
EINECS	Contact for details

Quality Control

Our 2,5-Dimethoxyphenylzinc Iodide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm identity, purity, and solution concentration (typically supplied as a solution in THF or other ethereal solvents). A comprehensive Certificate of Analysis (COA) detailing assay (by titration or ICP), residual solvent content, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This compound is easily oxidized and must be stored under an inert atmosphere (argon or nitrogen). For solutions, store at 2-8°C in the original sealed container. Keep away from heat, sparks, and open flame. Use appropriate ventilation and handling procedures for pyrophoric and moisture-sensitive materials.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Concentration	0.5 M in THF (or as specified)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.