Description

2-Chloro-6-Methylphenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically through Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity, reliable intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific chlorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Negishi Cross-Coupling Reactions: The primary application, facilitating efficient and selective coupling with various organic electrophiles like aryl halides.
• Catalyst & Ligand Preparation: Employed in the synthesis of complex ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Enables the production of specialty chemicals and complex fragrance or flavor molecules.

Basic Information

Product Name	2-Chloro-6-Methylphenylzinc Iodide
CAS No.	737797-38-5
Molecular Formula	C7H6ClIZn
Molecular Weight	317.87 g/mol
Synonyms	(2-Chloro-6-methylphenyl)zinc iodide; Zinc, (2-chloro-6-methylphenyl)iodo-; 2-Chloro-6-methylbenzenylzinc iodide; (2-Chloro-o-tolyl)zinc iodide; o-Chloro-o-tolylzinc iodide; 1-Chloro-2-methyl-6-(iodozincio)benzene; Iodo(2-chloro-6-methylphenyl)zinc
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Methylphenylzinc Iodide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including NMR and titration analysis, to ensure compliance with industry standards for high-purity organometallic reagents. Certificates of Analysis (COA) detailing purity, concentration, and solvent content are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed and handled in a dry, inert environment to prevent decomposition. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	Solution (typically in THF or ether)
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn basis)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.