Description

4-Phenoxybutylzinc Bromide is a highly reactive organozinc reagent, specifically a Grignard-type compound, widely used in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in the synthesis of complex organic molecules and pharmaceutical intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the introduction of the 4-phenoxybutyl moiety into target molecules during drug discovery and development.
• Negishi Cross-Coupling Reactions: Used as a nucleophilic coupling partner with various aryl, heteroaryl, and vinyl halides to construct complex carbon frameworks.
• Agrochemical Research: Employed in the synthesis of novel active ingredients for crop protection products.
• Liquid Crystal & OLED Material Production: Facilitates the synthesis of specialized organic compounds used in electronic displays and lighting.
• Polymer Modification: Acts as an initiator or functionalizing agent in the production of specialty polymers with tailored properties.
• Academic & Process R&D: A valuable tool for methodological development and scaling up synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	4-Phenoxybutylzinc Bromide
CAS No.	737797-32-9
Molecular Formula	C10H13BrOZn
Molecular Weight	294.51 g/mol
Synonyms	4-Phenoxybutylzinc bromide solution; Zinc, bromo(4-phenoxybutyl)-; (4-Phenoxybutyl)zinc bromide; Bromo(4-phenoxybutyl)zinc; 4-Phenoxybutyl zinc bromide; 1-Bromo-4-phenoxybutane zinc reagent; Phenoxybutylzinc bromide; Grignard reagent analog C10H13BrOZn
EINECS	Contact for details

Quality Control

Our 4-Phenoxybutylzinc Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, concentration, and purity, with a focus on maintaining optimal performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing assay, titration results, and solvent specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated area. This material is moisture-sensitive (hygroscopic) and easily oxidized; containers must be kept sealed and handled under inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (Typical)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Solvent Content (GC)	Meets specification

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.