Description

3,4-Dichlorobenzylzinc Chloride is a highly reactive organozinc reagent, specifically a benzylzinc halide, used in advanced organic synthesis. Its core value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which is critical for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable building blocks for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the 3,4-dichlorobenzyl moiety into target molecules during the research and development of new active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require the specific 3,4-dichlorobenzyl structural motif for biological activity.
• Cross-Coupling Reactions: Serves as a nucleophilic coupling partner in Negishi, Kumada, and related transition-metal-catalyzed cross-coupling reactions to form new C-C bonds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Material Science Research: Utilized in the synthesis of organic electronic materials, such as novel semiconductors or charge-transport layers, where specific halogenated benzyl groups are needed.
• Custom Chemical Synthesis: A valuable building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3,4-Dichlorobenzylzinc Chloride
CAS No.	737797-18-1
Molecular Formula	C7H5Cl3Zn
Molecular Weight	260.28 g/mol
Synonyms	(3,4-Dichlorobenzyl)zinc chloride; Zinc, (3,4-dichlorobenzyl)chloro-; 1-(Chlorozinciomethyl)-3,4-dichlorobenzene; (3,4-Dichlorophenyl)methylzinc chloride; 3,4-Dichlorobenzyl zinc chloride; Benzene, 1-(chlorozinciomethyl)-3,4-dichloro-; 3,4-DCBZnCl
EINECS	Contact for details

Quality Control

Every batch of 3,4-Dichlorobenzylzinc Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including titration for active zinc content and analytical techniques to confirm identity and purity, ensuring compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile and moisture-sensitive organometallic reagent, this material must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. The storage area must be cool, dry, and well-ventilated, away from sources of ignition and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF or as specified
Purity (GC/HPLC)	≥ 95% (by GC area)
Solvent	Typically Tetrahydrofuran (THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.