Description

2-Pentanone, 4-Amino-3-Methyl-, (3R,4S)-Rel- (9Ci) is a chiral, amino-functionalized ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, where its defined stereochemistry is critical for efficacy. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Synthesis: Acts as a building block for creating complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Development: Employed in the research phase for synthesizing new chiral herbicides or pesticides with improved selectivity.
• Academic & R&D Laboratories: Utilized in fundamental organic chemistry research to study reaction mechanisms and stereoselective transformations.

Basic Information

Product Name	2-Pentanone, 4-Amino-3-Methyl-, (3R,4S)-Rel- (9Ci)
CAS No.	735277-41-5
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(3R,4S)-4-Amino-3-methylpentan-2-one; rel-(3R,4S)-4-Amino-3-methyl-2-pentanone; 4-Amino-3-methyl-2-pentanone, (3R,4S)-rel-; Amino-methylpentanone; Chiral amino ketone intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this advanced intermediate, we provide comprehensive analytical data including chiral purity (enantiomeric excess) and chemical purity determined by HPLC, GC, and chiral chromatography. Certificates of Analysis (COA) with full spectral characterization (NMR, IR, MS) are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.