Description

cis-3-[2-Oxo-2-(2-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid is a high-value, synthetically derived organic compound featuring a cyclohexane carboxylic acid core linked to a trifluoromethylphenyl ketone moiety. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, or insecticides, leveraging the biological activity of the trifluoromethyl group.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study enzyme function or biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Material Science Research: Potential monomer or additive for developing specialty polymers with unique optical or surface properties.

Basic Information

Product Name	cis-3-[2-Oxo-2-(2-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735275-40-8
Molecular Formula	C₁₆H₁₇F₃O₃
Molecular Weight	314.30 g/mol
Synonyms	3-[2-Oxo-2-(2-Trifluoromethylphenyl)ethyl]cyclohexanecarboxylic acid (cis-); cis-3-(2-Oxo-2-(2-(trifluoromethyl)phenyl)ethyl)cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 3-[2-oxo-2-[2-(trifluoromethyl)phenyl]ethyl]-, cis-; CAS 735275-40-8; 2'-Trifluoromethylphenyl 3-carboxycyclohexyl ketone (cis-); (cis)-3-[2-Oxo-2-(2-trifluoromethyl-phenyl)-ethyl]-cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of cis-3-[2-Oxo-2-(2-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure traceability and compliance with your research or cGMP (current Good Manufacturing Practice) requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.