Description

trans-2-[2-(3-Chlorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for efficacy. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Core precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Chemical Research & Development: A valuable reagent for medicinal chemists exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs and CDMOs producing APIs for clinical trials and commercial supply.
• Academic Research: Employed in university and institutional labs for synthetic methodology development and pharmacological studies.

Basic Information

Product Name	trans-2-[2-(3-Chlorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735274-89-2
Molecular Formula	C15H17ClO3
Molecular Weight	280.75 g/mol
Synonyms	trans-2-(2-(3-Chlorophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; (1R,2R)-2-[2-(3-Chlorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; (1S,2S)-2-[2-(3-Chlorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; 3'-Chloro-2-oxo-2-phenylethyl-cyclohexanecarboxylic acid (trans); 735274-89-2; Cyclohexanecarboxylic acid, 2-[2-(3-chlorophenyl)-2-oxoethyl]-, trans-
EINECS	Contact for details

Quality Control

Our trans-2-[2-(3-Chlorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.