Description

cis-3-(2-Methylbenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise structural control for downstream processes. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex molecular architectures, leveraging both the carboxylic acid and ketone functionalities.
• Agrochemical Research: Serves as a precursor in the development of new generation herbicides or plant growth regulators with enhanced efficacy.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymeric materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	cis-3-(2-Methylbenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	735269-68-8
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	3-[(2-Methylphenyl)carbonyl]cyclohexanecarboxylic acid (cis-); cis-3-(2-Methylbenzoyl)cyclohexanecarboxylic acid; 1-Carboxy-3-(o-toluoyl)cyclohexane (cis-); (1r,3s)-3-(2-Methylbenzoyl)cyclohexane-1-carboxylic acid; (1s,3r)-3-(2-Methylbenzoyl)cyclohexane-1-carboxylic acid; 735269-68-8; cis-3-(o-Toluoyl)cyclohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our cis-3-(2-Methylbenzoyl)Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (cis-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.