Description

trans-2-(4-Chlorobenzoyl)Cyclopentane-1-Carboxylic Acid CAS NO 733741-02-1 is a high-purity, functionalized cyclopentane derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its molecular structure, featuring both a carboxylic acid and a chlorobenzoyl moiety, makes it a versatile synthon for constructing complex molecules with specific stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients requiring precise spatial orientation.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) agents, anti-inflammatory drugs, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators where the cyclopentane scaffold imparts specific biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and other fine chemicals due to its reactive functional groups.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and liquid crystals.
• Catalyst and Ligand Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	trans-2-(4-Chlorobenzoyl)Cyclopentane-1-Carboxylic Acid
CAS No.	733741-02-1
Molecular Formula	C13H13ClO3
Molecular Weight	252.69 g/mol
Synonyms	2-[(4-Chlorophenyl)carbonyl]cyclopentane-1-carboxylic acid (trans-); (1R,2S)-rel-2-(4-Chlorobenzoyl)cyclopentanecarboxylic acid; (1S,2R)-rel-2-(4-Chlorobenzoyl)cyclopentanecarboxylic acid; trans-2-(p-Chlorobenzoyl)cyclopentanecarboxylic Acid; 2-(4-Chlorobenzoyl)cyclopentane-1-carboxylic Acid; Cyclopentanecarboxylic acid, 2-(4-chlorobenzoyl)-, trans-; 733741-02-1; 4-Chloro-α-oxo-benzenepropanoic acid, γ-lactone (related form)
EINECS	Contact for details

Quality Control

Our trans-2-(4-Chlorobenzoyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acid nature, handle with appropriate engineering controls.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.